Replicating the Surgical “Gold Standard” by Utilizing a Synthetic TissueLining to Mimic Gastric Bypass via a Once-Daily Pill
- Utilizing a transient polydopamine polymer coating to precisely block nutrient absorption in the duodenum for 24 hours, providing a non-systemic “take-anytime” oral convenience that triggers the body’s natural satiety cascade (GLP-1 and PYY) without the gastrointestinal side effects of exogenous peptide hormones
- Matching the 1% weekly weight-loss efficacy observed in preclinical models while achieving 100% preservation of lean muscle mass, offering a potent oral alternative that solves the “muscle-wasting” crisis of current injectables and could capture significant market share among patients seeking “healthy” functional weight loss
- Optimizing the metabolic environment of the small intestine to ensure steady-state glycemic control and appetite suppression, bypassing the “peaks and troughs” of injectable delivery and establishing a sustainable, low-cost maintenance therapy that prevents the biological “rebound” of weight regain